Lipid metabolism in cultured cells. Activators of endogenous thromboxane A2 synthesis in cultured lung fibroblasts.
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چکیده
منابع مشابه
Lipid metabolism in cultured cells. Activators of endogenous thromboxane A2 synthesis in cultured lung fibroblasts.
Thromboxane A2 (rabbit aorta-contracting substance) is a proaggregatory vasoconstrictive, oxygenated metabolite of arachidonic acid which was originally discovered in guinea pig lung perfusates during antigen-induced anaphylaxis. The specific stimuli which activate synthesis and the cellular source in the lung remain undefined. In order to study pulmonary thromboxane A2 (TXA2) synthesis, a cult...
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Fatty acid and sterol biosynthesis were studied in several cell lines in culture. Two of these cell lines, L-M and NCTC 1469, demonstrated an 8.6and 7.2-fold increase, respectively, in acetate incorporation into fatty acids and a 5.2and 2.4-fold increase, respectively, in acetate incorporation into sterols within 24 hours after serum-containing medium was replaced with serum-free medium. Three ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1982
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)81036-0